Replaces proprietary alignment software for mapping DNA reads to large reference genomes. It utilizes SIMD instructions including AVX-512 to achieve 2x speedup over the original BWA-MEM algorithm.
Tech Stack
C++Biology & Biotechnology
Why bwa-mem2?
• Extreme SIMD optimization
• Low memory footprint for large genomes
• Backward compatible with BWA-MEM
Limitations
• Requires modern CPU instructions
• CLI only interface
• High RAM requirement for index
3/4/2026
Last Update
123
Forks
111
Issues
Other
License
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