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cogent3

The premium Open Source alternative to MEGA (Molecular Evolutionary Genetics Analysis)

🎯 Best for:Automated comparative genomics pipelines and custom evolutionary modeling.
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BSD-3-ClauseLicense

What is cogent3?

Replaces legacy tools like MEGA for large-scale evolutionary analysis and sequence alignment. Features a non-redundant object model for genomic features and high-performance likelihood calculations for phylogenetic trees.

Tech Stack
PythonBiology & Biotechnology

Why cogent3?

  • • Robust object-oriented design
  • • Extensive phylogenetic model support
  • • Excellent documentation and testing

Limitations

  • • Performance slower than C-based tools
  • • Complex API for simple tasks
  • • Dependency management can be tricky
3/6/2026
Last Update
67
Forks
34
Issues
BSD-3-Clause
License
Financial Leak Detected

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Competitor Cost
-$1,440
/ year (est. based on MEGA (Molecular Evolutionary Genetics Analysis))
Self-Hosted
$0
/ year
Team Size10 Users
150+
Launch Detailed Calculator
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