dorado

The premium Open Source alternative to ONT Guppy

🎯 Best for:Users of Oxford Nanopore devices requiring high-accuracy basecalling.

What is dorado?

Replaces legacy signal processing tools for converting raw nanopore electrical signals into DNA sequences. It utilizes PyTorch and custom CUDA kernels to maximize GPU throughput during real-time sequencing.

Tech Stack
C++Biology & Biotechnology

Why dorado?

  • State-of-the-art accuracy
  • Native GPU acceleration
  • Supports latest ONT chemistry

Limitations

  • Requires NVIDIA GPU
  • Large model downloads
  • Frequent update cycles
3/5/2026
Last Update
112
Forks
93
Issues
Other
License
Financial Leak Detected

Stop the "SaaS Tax"

Your team could be burning cash. Switching to dorado instantly boosts your runway.

Competitor Cost
-$1,440
/ year (est. based on ONT Guppy)
Self-Hosted
$0
/ year
Team Size10 Users
150+
SAVE 100%

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