← Back to Directory

Fragmenstein

The premium Open Source alternative to MOE

🎯 Best for:Fragment-based lead discovery and compound merging.
Visit WebsiteCompare with MOE
0.2k
Stars
MITLicense

What is Fragmenstein?

Replaces commercial fragment merging software like MOE. It uses a stitching algorithm to place compounds based on existing binding modes.

Tech Stack
PythonPharma & Biotechnology

Why Fragmenstein?

  • • Fast fragment merging
  • • Energy-aware
  • • Pythonic

Limitations

  • • Requires PyRosetta setup
  • • Niche use case
  • • Complex dependency chain
2/23/2026
Last Update
20
Forks
10
Issues
MIT
License
Financial Leak Detected

Stop the "SaaS Tax"

Your team could be burning cash. Switching to Fragmenstein instantly boosts your runway.

Competitor Cost
-$1,440
/ year (est. based on MOE)
Self-Hosted
$0
/ year
Team Size10 Users
150+
Launch Detailed Calculator
SAVE 100%

Community Discussion

Comments