muscle
The premium Open Source alternative to Geneious
🎯 Best for:Large-scale phylogenetic analysis
What is muscle?
Replaces proprietary sequence alignment software with a high-accuracy, scalable command-line tool. It utilizes a log-expectation score and tree-based refinement to handle thousands of sequences.
Tech Stack
C++Biology & Biotechnology
Why muscle?
- • High accuracy
- • Scalable to 10k+ sequences
- • Fast execution
Limitations
- • CLI only
- • No native GUI
- • Memory intensive
3/2/2026
Last Update
30
Forks
12
Issues
GPL-3.0
License
Financial Leak Detected
Stop the "SaaS Tax"
Your team could be burning cash. Switching to muscle instantly boosts your runway.
Competitor Cost
-$1,440
/ year (est. based on Geneious)
Self-Hosted
$0
/ year
Team Size10 Users
150+
SAVE 100%