ProLIF

The premium Open Source alternative to Schrödinger Maestro

🎯 Best for:Researchers analyzing non-covalent interactions in large molecular dynamics datasets.

What is ProLIF?

An alternative to commercial interaction analysis modules in Schrödinger Maestro. It automates the detection of hydrogen bonds, pi-stacking, and hydrophobic contacts from structural data.

Tech Stack
PythonBiology & Biotechnology

Why ProLIF?

  • Multi-frame MD analysis
  • Customizable interaction logic
  • Pandas integration

Limitations

  • Requires structural data
  • Learning curve for MDAnalysis
  • No native GUI
2/24/2026
Last Update
94
Forks
27
Issues
Apache-2.0
License
Financial Leak Detected

Stop the "SaaS Tax"

Your team could be burning cash. Switching to ProLIF instantly boosts your runway.

Competitor Cost
-$1,440
/ year (est. based on Schrödinger Maestro)
Self-Hosted
$0
/ year
Team Size10 Users
150+
SAVE 100%

Community Discussion

Comments