A high-performance alternative to standard BioPython sequence parsing. It uses C-based indexing to provide near-instant random access to sequences from plain or gzipped genomic files.
Tech Stack
CBiology & Biotechnology
Why pyfastx?
• Extremely fast indexing
• Low memory footprint
• Supports N50/L50 calculation
Limitations
• Index file creation overhead
• Limited to FASTA/Q formats
• C-extension compilation required
2/20/2026
Last Update
24
Forks
24
Issues
MIT
License
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