Replaces R-based GenomicRanges for high-performance genomic interval manipulation in Python environments. Uses Cython-backed interval trees to provide O(log n) overlap queries and efficient memory management.
Tech Stack
PythonBiology & Biotechnology
Why pyranges?
• Extremely fast interval overlaps
• Pandas-like intuitive API
• Low memory footprint for large datasets
Limitations
• Smaller ecosystem than R Bioconductor
• Requires Cython for compilation
• Limited visualization compared to R
2/26/2026
Last Update
50
Forks
93
Issues
MIT
License
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