sarek
The premium Open Source alternative to Sentieon
🎯 Best for:Standardized variant calling in clinical and research settings
What is sarek?
Replaces proprietary germline and somatic variant calling pipelines for whole-genome sequencing. Built on Nextflow to ensure full reproducibility and scalability across cloud and HPC environments.
Tech Stack
NextflowBiology & Biotechnology
Why sarek?
- • NF-Core certified pipeline
- • Supports multiple variant callers
- • Highly portable across clouds
Limitations
- • Requires Nextflow knowledge
- • Resource intensive
- • Complex configuration
3/3/2026
Last Update
526
Forks
274
Issues
MIT
License
Financial Leak Detected
Stop the "SaaS Tax"
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Competitor Cost
-$1,440
/ year (est. based on Sentieon)
Self-Hosted
$0
/ year
Team Size10 Users
150+
SAVE 100%