sarek

The premium Open Source alternative to Sentieon

🎯 Best for:Standardized variant calling in clinical and research settings

What is sarek?

Replaces proprietary germline and somatic variant calling pipelines for whole-genome sequencing. Built on Nextflow to ensure full reproducibility and scalability across cloud and HPC environments.

Tech Stack
NextflowBiology & Biotechnology

Why sarek?

  • NF-Core certified pipeline
  • Supports multiple variant callers
  • Highly portable across clouds

Limitations

  • Requires Nextflow knowledge
  • Resource intensive
  • Complex configuration
3/3/2026
Last Update
526
Forks
274
Issues
MIT
License
Financial Leak Detected

Stop the "SaaS Tax"

Your team could be burning cash. Switching to sarek instantly boosts your runway.

Competitor Cost
-$1,440
/ year (est. based on Sentieon)
Self-Hosted
$0
/ year
Team Size10 Users
150+
SAVE 100%

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