A multi-threaded Go application that annotates VCF files using data from multiple external genomic formats like BED and Tabix. It allows users to perform complex operations like min, max, or mean on overlapping genomic intervals.
Tech Stack
GoBiology & Biotechnology
Why vcfanno?
• Extremely fast multi-threaded execution
• No complex dependencies (single binary)
• Supports custom post-processing via Lua
Limitations
• Configuration files can be verbose
• Requires pre-indexed resource files
• Limited built-in biological effect prediction
2/24/2026
Last Update
56
Forks
37
Issues
MIT
License
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