The Showdown
Ensembl VEPvsvcfanno
Why pay monthly fees for Ensembl VEP when you can self-host vcfanno for free? Let's look at the facts.
VS
Ensembl VEP
The Expensive Option
- Closed Source (Black box)
- Expensive monthly fees per user
- Data stored on their servers
WINNER
vcfanno
The Freedom Choice
- 100% Open Source Code
- Free forever (Self-hosted)
- You own your data completely
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10 people
150100200+
$
*Estimated standard pricing for Ensembl VEP. Adjust if needed.
Estimated Annual Waste
$1,440
Monthly Burn Rate$120
5-Year Projection$7,200
Cost with Self-Hosted$0
Calculations based on 10 users at $12/mo.
Detailed Breakdown
0
Single-threaded or Perl-based
Native Go multi-threading
1
Fixed plugin architecture
Custom Lua scripting support
2
Slower interpreted execution
High-speed binary execution